Photopatterned Sacrificial Vascular Architectures for Large Tissue-Scale Oxygenation
Ian A. Coates, Carl A. Kohnke, Yee Lin Tan, Daniel I. Alnasir, Annie Nguyen, Elbert Heng, A. T. Kwan, Maria T. Dulay, Bruce T. Schaar, Mark A. Skylar‐Scott, John Ward MacArthur, Eric S. G. Shaqfeh, Joseph M. DeSimone
This paper introduces pCAST, a method to create perfusable vascular networks in 3D tissues, and shows it improves oxygen distribution and tissue viability.
bioRxiv · Mar 2, 2026 · PreprintBioengineering