Sertad4 regulates pathological cardiac remodeling.
Ashley Francois, Oscar Bermeo-Blanco, Bá Thông Nguyễn, Lynn M. Marcho, Anthony Elbon, Amrut V. Ambardekar, Yiqiang Zhang, Richard J. Gumina, Matthew S. Stratton
This study identifies Sertad4 as a fibroblast-specific regulator of cardiac fibrosis and remodeling, showing that its deletion reduces adverse outcomes after myocardial infarction.
bioRxiv · Mar 20, 2026 · PreprintPhysiology