Mathematical models disentangle the role of IL-10 feedbacks in human monocytes upon proinflammatory activation
Niloofar Nikaein, Kedeye Tuerxun, Gunnar Cedersund, Daniel Eklund, Robert L. Kruse, Eva Särndahl, Eewa Nånberg, Antje Thonig, Dirk Repsilber, Alexander Persson, Elin Nyman
The paper uses mathematical models to study IL-10 feedback mechanisms in human monocytes during inflammation, revealing their role in regulating TNF dynamics.
Journal of Biological Chemistry · Sep 1, 2023Peer-reviewedSystems Biology