Dirk Repsilber

Effects of incrementally increased plant-based protein intake on gut microbiota and inflammatory-metabolic biomarkers in healthy adults

This study examines how increasing pea protein intake affects gut microbiota and inflammatory biomarkers in healthy adults, finding changes in specific bacterial abundances and fecal markers.

Transcriptional modulation unique to vulnerable motor neurons predicts ALS across species and SOD1 mutations

The paper identifies gene expression patterns in motor neurons that predict ALS across species and SOD1 mutations, revealing differences in vulnerability and resilience.

Mathematical models disentangle the role of IL-10 feedbacks in human monocytes upon proinflammatory activation

The paper uses mathematical models to study IL-10 feedback mechanisms in human monocytes during inflammation, revealing their role in regulating TNF dynamics.

Healthspan pathway maps in C. elegans and humans highlight transcription, prolifera-tion/biosynthesis and lipids

The paper compiles healthspan-related gene pathways in C. elegans and humans using literature review and molecular interaction data, identifying common themes like transcription and lipids.

Capturing context-specific regulation in molecular interaction networks

The paper introduces a method to identify differentially activated subnetworks in molecular interaction networks, improving the detection of differential signals and describing regulated modules.