TET1 Functions as an Oxidized LDL Dependent Early-Stage Inducer of Atherosclerosis by Initiating Foam Cell Formation in Macrophages
Anvitha Boosani, Jonathan A. Green
This study identifies TET1's role in OxLDL-induced foam cell formation, a key early step in atherosclerosis, showing TET1's direct involvement while HDAC2 has an indirect role.
bioRxiv · Feb 7, 2026 · PreprintImmunology