UNWANTED AXON GROWTH: PTEN AND THE SUPPRESSION OF AXON PLASTICITY IN ADULT NERVES
Shane E. A. Eaton, Prashanth Komirishetty, Matt Larouche, Aparna Areti, Honyi Ong, Jose Martinez, Douglas William Zochodne
This paper shows that knocking out PTEN in adult sensory neurons of mice leads to increased axon sprouting and regenerative activity without affecting overall nerve function or behavior.
Experimental Neurology · May 25, 2026Peer-reviewedNeuroscience