BRAFV600E Expression in Mouse Neuroglial Progenitors Increase Neuronal Excitability, Cause Appearance of Balloon-like cells, Neuronal Mislocalization, and Inflammatory Immune response.
Roman U. Goz, Ari Silas, Sara Buzel, Joseph J. LoTurco
This study investigates how BRAFV600E mutation affects neuronal excitability and histopathological features in mouse cortical slices, showing increased excitability and balloon-like cell formation.
bioRxiv · Feb 15, 2019 · PreprintNeuroscience