No evidence for whole-chromosome dosage compensation or global transcriptomic expression differences in spontaneously-aneuploid mutation accumulation lines of Saccharomyces cerevisiae
Holly C. McQueary, Megan G. Behringer, Sam Demario, Alexander Joao Jamarillo Canas, Brittania Johnson, Ariella Tsfoni, John Chamberlin, David W. Hall
This study finds no whole-chromosome dosage compensation or global transcriptomic differences in aneuploid yeast lines, but detects gene-level expression attenuation and mutation accumulation effects.
bioRxiv · Dec 1, 2020 · PreprintGenetics