Direct lineage conversion of postnatal mouse cortical astrocytes to oligodendrocyte lineage cells
Justine Bajohr, E. Scott, Arman Olfat, Mehrshad Sadria, Kevin C. Lee, Maria Fahim, Hiba T Taha, Daniela Lozano Casasbuenas, Ann Derham, Scott A. Yuzwa, Gary D. Bader, Maryam Faiz
This study converts postnatal mouse astrocytes to oligodendrocyte lineage cells using Sox10 or Olig2, supported by single-cell RNA sequencing and computational models.
bioRxiv · May 28, 2024 · PreprintDevelopmental Biology