Parent-of-origin phasing of somatic mutations shows equal mutation burden between parental genomes in human cancers
Maxime Lefebvre, Arnaud Cleris, Mathieu Parmentier, Peter Van Loo, Vincent Detours, Maxime Tarabichi
The paper quantifies parental mutation burden symmetry in human cancers using PhaSoMix, finding near-equal mutation accumulation between maternal and paternal genomes.
bioRxiv · Sep 7, 2026 · PreprintGenomics