Deletion of FUNDC2 and CMC4 on chromosome Xq28 is sufficient to cause hypergonadotropic hypogonadism in men
Xinxian Deng, He Fang, Asha Pathak, Angela M. Zou, Whitney Neufeld‐Kaiser, Emily A. Malouf, R. Alan Failor, Fuki Marie Hisama, Yajuan J. Liu
This study identifies a deletion of FUNDC2 and CMC4 on Xq28 as sufficient to cause hypergonadotropic hypogonadism in men by disrupting apoptosis, inflammation, and FSH regulation.
Frontiers in Genetics · Sep 22, 2020Peer-reviewedGenomics