Astrocyte sensitivity to glymphatic shear stress is amplified by albumin and mediated by the interaction of sphingosine 1 phosphate with Piezo1
David Ballesteros-Gomez, Sean McCutcheon, Greta L. Yang, Antonio Cibelli, Ashley Bispo, Michael B Krawchuk, Giselle Piedra, David Conover Spray
The paper investigates how astrocytes respond to glymphatic shear stress, finding that albumin enhances sensitivity through S1P-Piezo1 signaling.
bioRxiv · Nov 6, 2023 · PreprintNeuroscience