Utility of the Recombinase Driver CX3CR1::Cre Rat Strain to Evaluate Microglial Contributions to Nicotine Addiction
Ashley M. White, Ashley J Craig, Daryl L Richie, Christa L. Corley, Emma O. Bondy, Percell T. Kendrick, Haley McManus, Safiyah M. Sadek, Michael D. Scofield, Cassandra D. Gipson
This study validates a CX3CR1::Cre transgenic rat line for investigating microglial roles in nicotine self-administration by demonstrating DREADD transduction and nicotine SA behavior.
bioRxiv · Mar 18, 2025 · PreprintNeuroscience