Surface Display For Phage Assisted Continuous Evolution: A Platform For Evolving / Screening Nanobodies In Prokaryote Systems
Fernando Flores-Mora, Jennifer Brodsky, Ashley Tse, Rory Hoover, Gabrielle Cerna, Benjamin B. Bartelle
The paper introduces SurPhACE, a platform that evolves nanobodies in prokaryote systems by combining surface and phage display, achieving high throughput and efficient mutation turnover.
bioRxiv · Apr 4, 2026 · PreprintSynthetic Biology