Dynamics of a hepatocyte-cholangiocyte decision-making gene regulatory network during liver development and regeneration
Sarthak Sahoo, Ashutosh Mishra, Anna Mae Diehl, Mohit Kumar Jolly
The paper identifies a gene regulatory network governing hepatocyte-cholangiocyte fate decisions during liver development and regeneration, revealing its multistable dynamics and ability to predict cell-state transitions.
iScience · Aug 17, 2022Peer-reviewedDevelopmental Biology