Anna Mae Diehl

This study shows that mitochondrial copper deficiency drives MASLD by causing ferroptosis, senescence, and fibrosis, and that restoring copper homeostasis can alleviate disease.

The paper identifies dysregulated RNA splicing in alcohol-associated liver disease as a cause of regeneration failure, highlighting ESRP2 deficiency and its impact on key signaling pathways.

The paper identifies a gene regulatory network governing hepatocyte-cholangiocyte fate decisions during liver development and regeneration, revealing its multistable dynamics and ability to predict cell-state transitions.

This study identifies a molecular pathway involving ARRB2 and RARRES1 that regulates the transition from liver fibrosis to cancer, with implications for diagnostics and therapeutics.