Prediction and in vitro silencing of two lipid biosynthetic genes viz. SCD and SREBP1 in chicken using RNA interference
N. Govardhana Sagar, Athe Rajendra Prasad, RUDRA NATH CHATTERJEE, T Vijaya Kumar, Bharat Bhushan, P. Guru Vishnu, T. K. Bhattacharya
The paper designs and tests shRNA molecules to silence SCD and SREBP1 genes in chicken hepatocytes, showing varying knockdown efficiencies with some molecules achieving over 95% reduction.
bioRxiv · Oct 21, 2020 · PreprintMolecular Biology