Shifted Reverse PAGE: a novel approach based on structure switching for the discovery of riboswitches and aptamers
Aurélie Devinck, Emilie Boutet, Jonathan Ouellet, Rihab Rouag, Balasubramanian Sellamuthu, Jonathan Perreault
This paper introduces SR-PAGE, a method to discover riboswitches and aptamers by detecting conformational changes in RNA upon ligand binding.
bioRxiv · Jul 26, 2022 · PreprintMolecular Biology