Activity-induced weakening of hippocampal input to prefrontal VIP interneurons reshapes inhibitory microcircuit function: implications for spatial working memory task acquisition
Shana E. Silverstein, Thomas T. Clarity, Meena S. Deshpande, Erik Vaughan, Shoshana Novik, Héctor E. Yarur, Shiliang Zhang, Valerie S. Tsai, Rong Ye, Rachel M. Mikofsky, Madeline Hsiang, Avery Bauman, Gabriel C. Loewinger, Francisco Lucas F. Pereira, Marisela Morales, , David A. Kupferschmidt
The paper investigates how hippocampal input to prefrontal VIP interneurons changes with activity and affects spatial working memory task learning in mice.
bioRxiv · Jul 21, 2025 · PreprintNeuroscience