Massive influence of DNA isolation and library preparation approaches on palaeogenomic sequencing data
Axel Barlow, Gloria G. Fortes, Love Dalén, Ron Pinhasi, Boris Gasparyan, Gernot Rabeder, Christine Frischauf, Johanna L.A. Paijmans, Michael Hofreiter
This study shows that DNA isolation and library preparation methods greatly affect palaeogenomic data quality and interpretation.
bioRxiv · Sep 19, 2016 · PreprintGenomics