Glycerol suppresses lactose-dependent growth of Streptococcus pyogenes through a transcription-independent mechanism
Ayako Bando, Yujiro Hirose, Olivia M. Bertolla, Norihiko Takemoto, Stephan Brouwer, Jack O’Donohue, Masayuki Ono, Eri Ikeda, Victor Nizet, Mark J. Walker, Shigetada Kawabata
This study shows glycerol inhibits lactose-dependent growth in Streptococcus pyogenes without affecting transcription, while lactose induces distinct transcriptional responses.
bioRxiv · Nov 24, 2025 · PreprintMicrobiology