Genome editing of the flavanone 3-hydroxylase gene produces a green Perilla line with elevated luteolin accumulation
Shuji Matsushita, Michiharu Nakano, Suguru Chokyuu, Masaki Kurao, Ayane Fujita, Junko Kimura, Chinatsu Nagata, Takeshi Ishikawa, Keita Tamura, Hidemasa U. Bono
This study uses CRISPR-Cas9 to edit the F3H gene in Perilla, resulting in green plants with increased luteolin accumulation and reduced anthocyanin production.
bioRxiv · Dec 28, 2025 · PreprintPlant Biology