Long G4-rich enhancer physically interacts with EXOC3 promoter via a G4:G4 DNA-based mechanism
Jeffrey D. DeMeis, Justin T. Roberts, Haley A Delcher, Noel L Godang, Alexander B. Coley, Cana L. Brown, Michael H Shaw, Sayema Naaz, Enas S. Alsatari, Ayush Dahal, Shahem Y Alqudah, Kevin N Nguyen, Anita D Nguyen, Sunita S. Paudel, Hong Dang, , Glen Mark Borchert
The paper identifies LG4 enhancers that physically interact with gene promoters via G4:G4 DNA structures and links SNPs in these enhancers to CF lung disease severity.
bioRxiv · Jan 29, 2024 · PreprintGenetics