Neovascularization and the recruitment of CD31+ cells from the bone marrow are unique under regenerative but not wound repair conditions
Kamila Bedelbaeva, Young Zhang, Azamat Azlanukov, Dmitri Gourevitch, Iossif A. Strehin, Phillip B. Messersmith, Ellen Heber‐Katz
This study shows endostatin inhibits epimorphic regeneration in mice by blocking bone marrow-derived CD31+ endothelial precursor recruitment, unlike its effect on wound repair.
bioRxiv · Mar 2, 2022 · PreprintDevelopmental Biology