Molecular Characterization of SARS-CoV-2 N Protein Interfaces: Implications for Oligomerization, RNA Binding, and Phase Separation
Sneha G. Bairy, T.K. Prasad, Yogeshwar Saravana Kumar, B. Ganavi, S Shwetha, S Saranya, B Sriram Prakash, Vignesh Sounderrajan, Krupakar Parthasarathy, Neelagandan Kamariah
This study characterizes the molecular interfaces of the SARS-CoV-2 N protein's CTD and flanking IDRs, revealing their roles in oligomerization, RNA binding, and phase separation.
bioRxiv · Mar 6, 2026 · PreprintBiophysics