A Spectroscopic Approach to Unravel the Local Conformations of G-quadruplex Using CD-active Fluorescent Base Analogues
D. Jose, M. M. Michael, C. Bentsen, B. C. Rosenblum, A. Zelaya
This study uses CD-active fluorescent base analogues to monitor local conformational changes in G-quadruplex structures, providing insights into small molecule-GQ interactions and potential drug design applications.
bioRxiv · Jul 6, 2022Biochemistry