ATR-I774Yfs*5 promotes genomic instability through micronuclei formation
J. D'Orazio, N. Holcomb, H. Pu, B. Dhar, R. Bautista, A. Overmann, B. Shelton, L. Corum
This study shows that the ATR-I774Yfs*5 mutation promotes genomic instability through micronuclei formation in MMR-defective cancers.
bioRxiv · Mar 10, 2022 · PreprintCancer Biology