Binding of synGAP to PDZ Domains of PSD-95 is Regulated by Phosphorylation and Shapes the Composition of the Postsynaptic Density
Ward G. Walkup, Tara Mastro, Leslie T. Schenker, Jost Vielmetter, Rebecca Hu, Ariella Iancu, Meera Reghunathan, B. Dylan Bannon, B. Kennedy Mary
This study shows phosphorylation of synGAP by CaMKII reduces its binding to PSD-95 PDZ domains, altering the composition of the postsynaptic density.
bioRxiv · Jun 9, 2016 · PreprintNeuroscience