Author

B. E. Shipley

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1 Approach:simulation· 1

Frequent Co-Authors

K. Surewicz· 1 shared M. Hinczewski· 1 shared R. Haider· 1 shared W. K. Surewicz· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiophysics

K. Surewicz

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1 paper

Recent·Most cited

Pathological C-terminal phosphomimetic substitutions alter the mechanism of liquid-liquid phase separation of TDP-43 low complexity domain

R. Haider, B. E. Shipley, K. Surewicz, M. Hinczewski, W. K. Surewicz

This study investigates how phosphomimetic substitutions at C-terminal sites of TDP-43's low complexity domain alter liquid-liquid phase separation, revealing a biphasic salt dependence and changes in phase separation mechanisms.

bioRxiv · Mar 21, 2024Biophysics