Protein-Folding Chaperones Predict Structure-Function Relationships and Cancer Risk in BRCA1 Mutation Carriers
B. Gracia, P. Montes, A. M. Gutierrez, B. Arun, G. I. Karras
This study uses chaperone interactions to predict pathogenicity and cancer risk in BRCA1 mutation carriers by assessing structural and phenotypic defects.
bioRxiv · Sep 14, 2023 · PreprintBiochemistry