Three-dimensional imaging and single-cell transcriptomics of the human kidney implicate perturbation of lymphatics in alloimmunity
D. J. Jafree, B. Stewart, M. Kolatsi-Joannou, B. Davis, H. Mitchell, L. G. Russell, L. Marinas del Rey, W. J. Mason, B. I. Lee, L. Heptinstall, G. Pomeranz, D. Moulding, L. Wilson, T. Wickenden, S. Malik, , D. A. Long
This study uses 3D imaging and single-cell RNA-sequencing to analyze human kidney lymphatics, revealing structural and transcriptional changes in rejecting kidney transplants.
bioRxiv · Oct 28, 2022 · PreprintImmunology