Author

B. Ozguney

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Biophysics· 1

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Approach:biophysical modeling· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

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J. Mittal· 1 shared P. Mohanty· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperBiophysics

J. Mittal

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1 paper

Recent·Most cited

RNA-binding tunes the conformational plasticity and intradomain stability of TDP-43 tandem RNA recognition motifs

B. Ozguney, P. Mohanty, J. Mittal

This study uses molecular dynamics simulations to show RNA-binding stabilizes TDP-43 tandem RRMs and reduces conformational plasticity, preventing pathological aggregation.

bioRxiv · Feb 25, 2024Biophysics