The P450 Sterol Side Chain Cleaving Enzyme (P450scc) for Digoxin Biosynthesis in the Foxglove Plant Belongs to the CYP87A Family
E. Carroll, B. Ravi Gopal, I. Raghavan, Z. Q. Wang
The paper identifies the P450scc enzyme in foxglove responsible for digoxin biosynthesis, showing it belongs to the CYP87A family and converts cholesterol and campesterol to pregnenolone.
bioRxiv · Dec 29, 2022 · PreprintPlant Biology