Integrative computational approach identifies new targets in CD4+ T cell-mediated immune disorders
Bhanwar Lal Puniya, Rada Amin, Bailee Lichter, ROBERT E. MOORE, Alex Ciurej, Sydney J. Bennett, Ab Rauf Shah, Matteo Barberis, Tomáš Helikar
The paper identifies 68 potential drug targets for three autoimmune diseases by integrating genome-scale metabolic models with gene expression data and in vitro validation.
npj Systems Biology and Applications · Jan 22, 2021Peer-reviewedSystems Biology