LSR Targets YAP to Modulate Intestinal Paneth Cell Differentiation
Yanan An, Chao Wang, Baozhen Fan, Ziqi Wang, Ying Li, Feng Kong, Chengjun Zhou, Zhang Cao, Mingxia Wang, Hui Sun, Shengtian Zhao, Yongfeng Gong
This study identifies LSR as a negative regulator of YAP activity, essential for Paneth cell differentiation and a potential therapeutic target for inflammatory bowel disease.
Cell Reports · Sep 1, 2023Peer-reviewedDevelopmental Biology