Kir4.2 deficiency drives progressive Parkinson's disease-like motor, cognitive and neuropathological phenotypes in mice
Benjamin Garland, Zhiqiang Shen, Mo Chen, Bo Gao, Kailin Mao, Des Raymond Richardson, George D. Mellick, Linlin Ma
This study shows that Kir4.2 deficiency in mice causes PD-like motor, cognitive, and neuropathological symptoms, establishing a new model for PD research.
bioRxiv · May 4, 2026 · PreprintNeuroscience