Intra-Abdominal Photodynamic Therapy in a Rabbit Model of Perforated Appendicitis
Timothy M. Baran, Korry T. Wirth, Matthew Byrne, Benjamin Gersten, Eric Y. Wang, Darrian S. Hawryluk, Martin S. Pavelka, Nicole A. Wilson
This paper evaluates the feasibility and safety of laparoscopic methylene blue photodynamic therapy (MB-PDT) in a rabbit model of perforated appendicitis, showing no off-target injury and in vitro antimicrobial efficacy.
bioRxiv · Sep 24, 2025 · PreprintMicrobiology