A stress-activated mid-insula to BNST pathway regulates susceptibility to abstinence-induced negative affect in female mice
Benjamin M. Williams, Jincy R. Little, Nathaniel Sean O'Connell, Samuel W. Centanni
This study identifies a mid-insula to BNST neural circuit that drives stress susceptibility and negative affect during abstinence in female mice, suggesting it as a therapeutic target for AUD.
bioRxiv · Jan 7, 2025 · PreprintNeuroscience