Targeting miRNA for Colorectal Cancer: In Silico Identification and Physics-based De Novo Modeling of Oncogenic miR-135b for Small Molecule RNA Therapy
Berat Demir, Lalehan Oktay, Serdar Durdağı
The paper identifies miR-135b as a differentially expressed miRNA in colorectal cancer and models small molecule ligands targeting its Dicer cleavage site using computational methods.
bioRxiv · Jun 8, 2024 · PreprintBioinformatics