Towards development of a statistical framework to evaluate myotonic dystrophy type 1 mRNA biomarkers in the context of a clinical trial
Adam Kurkiewicz, Anneli Cooper, Emily McIlwaine, Sarah A. Cumming, Berit Adam, Ralf Krahe, Jack Puymirat, Benedikt G. H. Schoser, Lubov Timchenko, Tetsuo Ashizawa, Charles A. Thornton, Simon Rogers, John McClure, Darren G. Monckton
The paper develops a statistical framework to evaluate mRNA biomarkers for DM1 treatment efficacy using machine learning and microarray data.
PLoS ONE · Apr 14, 2020Peer-reviewedBioinformatics