A Genome-Wide Association Study Reveals Novel Genetic Markers Associated with Human African Trypanosomiasis
Julius Mulindwa, Magambo Phillip Kimuda, Harry A. Noyes…·Enock Matovu
Author
University of GlasgowORCID 0000-0002-1159-142XUnclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
6 papers
Recent·Most cited
Julius Mulindwa, Magambo Phillip Kimuda, Harry A. Noyes…·Enock Matovu
John O. Ogunsola, Anneli Cooper, Juan F. Quintana, Annette MacLeod
This study shows that Trypanosoma brucei infection in mice causes kidney injury with transcriptomic features similar to acute kidney injury.
Walt E. Adamson, Harry A. Noyes, John O. Ogunsola…·Annette MacLeod
This study uses UK Biobank data to show APOL1 genotype strongly influences plasma APOL1 levels, with Black or Black British individuals having higher levels despite genetic variation.
Walt E. Adamson, Harry A. Noyes, P. Johnson…·Annette MacLeod
This study identifies non-kidney disease associations with APOL1 G1/G2 compound heterozygosity and reveals distinct effects of G1 and G2 homozygosity on kidney-related outcomes.
Adam Kurkiewicz, Anneli Cooper, Emily McIlwaine…·Darren G. Monckton
The paper develops a statistical framework to evaluate mRNA biomarkers for DM1 treatment efficacy using machine learning and microarray data.
Paul Capewell, Bruno Bucheton, Caroline Clucas…·Annette MacLeod
The paper identifies genetic factors and immune mechanisms associated with symptom severity in human African trypanosomiasis using transcriptome analysis and an animal model.