The exosomes derived from urine of premature infants target MAPK8 via miR-30a-5p to protect cisplatin-induced acute kidney injury in mice
Mingming Ma, Qiao Luo, Lijing Fan, Weilong Li, Qiang Li, Yu Meng, Chen Yun, Hongwei Wu, Yongping Lu, Shuang Cui, Fanna Liu, Bo Hu, Baozhang Guan, Huanhuan Liu, Shengling Huang, , Berthold Hocher
This study shows that exosomes from premature infant urine reduce cisplatin-induced acute kidney injury in mice by delivering miR-30a-5p, which targets MAPK8 to prevent apoptosis.
bioRxiv · Aug 29, 2021 · PreprintMolecular Biology