Converging effects of cannabis and psychosis on the dopamine system: A longitudinal neuromelanin-sensitive MRI study in cannabis use disorder and first episode schizophrenia.
Jessica Ahrens, Sabrina D. Ford, Betsy Schaefer, David Reese, ALI RAZA KHAN, Philip G. Tibbo, Rachel Allison Rabin, Clifford Cassidy, Lena K. Palaniyappan
This study uses neuromelanin-MRI to show that cannabis use disorder is associated with elevated dopamine signaling in specific midbrain regions, suggesting shared mechanisms with psychosis.
bioRxiv · Sep 12, 2024 · PreprintNeuroscience