GenomicsbioRxivPreprint
Moving Beyond Binary Biomarkers: Machine Learning Model Resolves Concurrent and Molecularly Heterogeneous Mismatch Repair and Homologous Recombination Deficiencies in Prostate Cancer
Komal Sharma, Divin A. Wilson, Yu Wang…·Navonil De Sarkar
This paper develops a machine learning model to identify molecularly distinct DDR subgroups in prostate cancer, revealing concurrent repair deficiencies and improving therapeutic stratification.
DOI 10.1101/2025.10.08.680958