Yu Wang

LANTERN: Leveraging Local Ancestry Tracts to Enhance Rare-Variant Aggregate Association Testing

LANTERN improves rare-variant association testing in admixed populations by incorporating local ancestry information, identifying ancestry-specific associations in a cohort of African Americans.

Moving Beyond Binary Biomarkers: Machine Learning Model Resolves Concurrent and Molecularly Heterogeneous Mismatch Repair and Homologous Recombination Deficiencies in Prostate Cancer

This paper develops a machine learning model to identify molecularly distinct DDR subgroups in prostate cancer, revealing concurrent repair deficiencies and improving therapeutic stratification.

A Metagenomic Approach Does Not Elucidate Uremic Toxin Levels in Hemodialysis Patients.

This study investigates the relationship between fecal microbiome and serum uremic toxins in hemodialysis patients, finding that dietary protein-to-fiber ratio, not microbiome composition, is significantly associated with toxin levels.