A pro-oxidant combination of resveratrol and copper down-regulates multiple biological hallmarks of ageing and neurodegeneration
Kavita Pal, Gorantla Venkata Raghuram, Jenevieve Dsouza, Sushma Shinde, Vishalkumar Jadhav, Alfina Shaikh, Bhagyeshri Rane, Harshali Tandel, Dipali Kondhalkar, Shahid Chaudhary, Indraneel Mittra
The paper shows that resveratrol and copper reduce multiple ageing and neurodegeneration markers by deactivating cell-free chromatin particles in mice.
bioRxiv · May 4, 2022 · PreprintNeuroscience