Plasmid conjugation drives within-patient plasmid diversity
Fan Grayson, Leo Loman, Toby Nonnenmacher, Diane Pople, Jack Pollard, Bharat Patel, David Williams, Luke S. Hounsome, Katie L. Hopkins, Julie V. Robotham, Alice Ledda
This study shows that plasmid conjugation is the main driver of within-patient plasmid diversity, as most patients share identical OXA-48 plasmids across different bacterial hosts.
Microbial Genomics · Mar 20, 2025Peer-reviewedBioinformatics