Mgat4b mediated selective N-glycosylation regulates melanocyte development and melanoma progression
Babita Sharma, Keerthic Aswin, Tanya Jain, Ayesha Nasreen, Ayush Aggarwal, Yogaspoorthi J. Subramaniam, Jeyashri Rengaraju, Srashti Jyoti Agrawal, Mayank Bhatt, Bhashkar Paul, Koushika Chandrasekaran, Aanchal Yadav, Jyoti Soni, Rajat Ujjainiya, Md Quasid Akhter, , Vivek T. Natarajan
This study identifies Mgat4b as a regulator of melanocyte development and melanoma progression through N-glycosylation, showing its role in cell migration, adhesion, and tumor initiation.
Proceedings of the National Academy of Sciences · May 27, 2025Peer-reviewedCancer Biology