Chromatin Loops as Allosteric Modulators of Enhancer-Promoter Interactions
Boryana Doyle, Geoffrey Fudenberg, Maxim Imakaev, Leonid Mirny
The paper uses polymer simulations to show that chromatin loops can either insulate or facilitate enhancer-promoter interactions, depending on their location relative to the pair.
PLoS Computational Biology · Oct 23, 2014Peer-reviewedBiophysics