Boryana Doyle

A microproteome screen identifies immunomodulatory bacterial microproteins encoded in expanded gene arrays in Leptotrichia

The paper identifies immunomodulatory bacterial microproteins from Leptotrichia using a microproteome screen and shows they influence macrophage polarization.

Replicative selfish genetic elements are driving rapid pathogenic adaptation of Enterococcus faecium

This study identifies ISL3 elements as drivers of rapid genomic evolution in E. faecium, enabling metabolic adaptation in clinical settings through structural variation and gene regulation.

Differential effects of two common GVHD prophylaxis regimens on the gut microbiome: Results from the BMT CTN 1801 study

This study compares the effects of two GVHD prophylaxis regimens on the gut microbiome in allo-HCT recipients and finds that while PTCy reduces microbiome diversity and bile acid metabolism, it is linked to better clinical outcomes.